How does Ketamine work?

pexels cottonbro studio 6491257 by Voyage Healing in Philadelphia, PA

Ketamine, an FDA approved anesthetic agent, is being used off label to treat a variety of mental health issues.  While there is the most research for treatment refractory depression (including bipolar depression), suicidal ideation, PTSD, and addiction, there is also research suggesting beneficial effects for OCD, anxiety, eating disorders, and end of life care.     A Unique Mechanism of Action:     Compared to other antidepressants, ketamine has a unique mechanism of action.  Whereas most antidepressants affect levels of serotonin, ketamine works on a different receptor, called the NMDA receptor.  The NMDA receptor plays a role in […]